After making significant advancements in HIV and COVID-19 research, Virongy, a biotechnology company in Prince William County, Virginia, has set its sight on tackling even more viruses. With millions of people being afflicted by viral illnesses worldwide each year, Virongy’s objective addresses an ever-increasing market need.
"Our goal is to create advanced diagnostics so that doctors can promptly prescribe treatments to patients,” said Brian Hetrick, chief scientific officer of Virongy.
The Virongy team also works beyond the walls of their commercial lab, leveraging the unique infectious disease research capabilities offered by George Mason University’s Biomedical Research Laboratory on the Science and Technology Campus in Manassas.
This state-of-the-art building, where studies can be conducted safely and in compliance with Centers for Disease Control and Prevention regulations, provides an ideal place for them to work on Biosafety Level 3 (BSL3) pathogens. Pathogens investigated in a BSL3 laboratory have the possibility to cause serious or potentially lethal disease through respiratory transmission.
Yuntao Wu, a professor in the College of Science (COS) and a member of the Institute for Biohealth Innovation at Mason, founded Virongy in 2013. The biotech company was formed after Wu licensed an HIV drug-screening technology that was developed in his Mason lab. From there, he was able to set up his new company at the Prince William County Science Accelerator, a life sciences startup incubation facility.
“Virongy’s success in addressing worldwide pervasive viruses such as HIV and COVID-19, and now its move to expand its scope to a larger variety of diseases, is an achievement we are immensely proud of here at Mason,” said COS Dean Fernando Miralles-Wilhelm.
Recognizing the technology’s tremendous potential, angel investors and venture capitalists sought out Virongy for investment. The company also has been the recipient of multiple nondilutive grants, including a Prince William County Department of Economic Development (PWCDED) IGNITE program grant and a Small Business Innovation Research (SBIR) grant through the National Institutes of Health.
In 2021, Virongy Biosciences won an IGNITE program grant, a competitive non-dilutive cash grant offered by PWCDED for early-stage startups and emerging companies.
With its rapid growth, Wu knew Virongy needed more space. The opening of the Northern Virginia Bioscience Center, a 30,000-square-foot wet lab building managed by Holladay Properties with sophisticated equipment funded by GO Virginia, brought Wu his answer.
The Biohealth Capital Region, comprising Virginia, Maryland, and Washington D.C., is the fourth-ranked biopharma cluster in the United States, as reported by Genetic Engineering and Biotechnology News. The region’s high concentration of talent in the health care sector meant that additional commercial wet lab space was a necessity.
In May 2022, Virongy announced a $471,000 expansion with up to 70 new jobs for the company as part of Virginia Jobs Investment Program (VJIP), which provides consultative services and funding to companies creating new jobs in order to support employee recruitment and training activities.
"Disruption is always an opportunity for innovation, and our life sciences sector in Prince William County expanded exponentially during the pandemic,” said Christina Winn, executive director of the PWCDED. "Virongy’s expansion is a combination of exciting technology from Dr. Wu with the addition of expert business staff and the lab space to grow right here in Innovation Park."
The launching of the bioscience center allowed Virongy to move from a 600-square-foot space to a 1,600-square-foot lab. Both Wu and Hetrick are excited about the opportunities that come with the expansion.
"Not only can we bolster our research capabilities, but we also aim to be a supplier of new jobs in the area," said Hetrick, who holds a PhD in biosciences from Mason.
In addition, Virongy is one of the life science companies that is part of the Northern Virginia BioHub, which was recently established through Virginia Bio-Connect and funded by a $3.2 million GO Virginia matching grant. Susan Baker, managing director of GO Virginia’s Region 7, sees the grant as money well-invested.
"Projects like these are extremely important for economic growth and talent development of high-wage jobs in our region," said Baker.
While the move has kept them busy, Virongy has no plans to slow down. One of its next steps includes obtaining Good Manufacturing Practices (GMP) certification in order to open a GMP lab. The certification ensures that all products produced in the lab are safe and effective, and expedites the FDA approval process for any products the company intends to bring to market. Virongy anticipates having GMP certification within the next several months.
"We constantly strive to bring forward innovative solutions that break past limitations of existing technologies,” said Wu. “If there is a faster way to tackle some of global health’s most pressing challenges, we will do it."
A version of this story originally appeared on the George Mason University news blog in May 2022 and is republished with permission.
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